Study takes step toward erasing bad memories

brainscan

via Reuters

LONDON (Reuters) – A widely available blood pressure pill could one day help people erase bad memories, perhaps treating some anxiety disorders and phobias, according to a Dutch study published on Sunday.

The generic beta-blocker propranolol significantly weakened people’s fearful memories of spiders among a group of healthy volunteers who took it, said Merel Kindt, a psychologist at the University of Amsterdam, who led the study.

“We could show that the fear response went away, which suggests the memory was weakened,” Kindt said in a telephone interview.

The findings published in the journal Nature Neuroscience are important because the drug may offer another way to help people suffering from post-traumatic stress disorder and other problems related to bad memories.

Traditionally, therapists seek to teach people with such disorders strategies to build new associations and block bad memories. The problem, Kindt said, is the memories remain and people often relapse.

Animal studies have shown that fear memories can change when recalled, a process known as reconsolidation. At this stage they are also vulnerable to beta-blockers like propranolol, which target neurons in the brain, the researchers said. Continue reading